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TRANSVERSE
MYELITIS
Transverse myeltis is a condition
that results in the inflammation of the myelin sheath of the spinal
cord. The area targeted goes across the width of the spinal cord at
a certain level of the spinal cord. The problem occurs after vaccines
(DPT, Influenza etc. , viral infections, post radiation treatments.
The underlying problem is that certain elements of the patient’s
own immune system cause inflammation and sometimes destruction of the
myelin.
Symptoms include pain in the arms, legs, back and neck; numbness, paresthesias,
numbness below the affected area of the spinal cord; weakness of the
arms and legs; muscle spasms; headache.
Tests may include lumbar spinal tap; functional MRI; NMO-IgG test.
Many patients will clear up uneventfully after the acute phase; others
may have relapses; some patients may go into a chronic phase with partial
or total paralysis of the upper and lower extremities; spasticity; osteoporosis
and sexual dysfunction.
Treatment initially should include intravenous cortisone. If symptoms
continue plasma exchange therapy (apheresis) is considered. If the condition
does not improve StemCellGeneNano recommends the following:
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Autologous stem cells.
The patient is given an injection of G-CSF once daily for three days.
Peripheral blood or a bone marrow aspirate is withdrawn and in the
laboratory autologous stem cells are extracted and administered to
the patient.
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Following this the patient
is given by spinal canal administration at the level of disease neuron
stem cells mixed with neurotrophins, nerve cell factor, neuropeptide
protein, glial derived neurotrophins oligodendrocytes. In addition
the following may be given riluzole that targets sodium dysregulation
in the affected spinal cord; minocycline that targets apoptosis and
neuroinflammation.
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Targeting immune factors
include anti-IL-6; anti-TNF; IL-17 and IL-1beta which attack the myelin
in this condition.
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Targeting axonal inhibitors
such as Rho with Cethrin and ATI-355 against Nogo.
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Electric field stimulation.
Medical Disclaimer: Treatments discussed
on this website are experimental and have not been approved by the FDA.
No guarantees are made regarding the results of these treatments. Prospective
patients are advised to discuss the use of a Stem Cell treatment for their
disease with their physician.
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